The Resident Evil series has long been renowned for its exceptional boss designs, with developer Capcom consistently delivering high-quality boss fights. The franchise has featured a wide range of creatures, like eldritch monstrosities, super soldiers from the undead, and huge animals. Let's delve into the Resident Evil universe and explore the 10 most powerful bosses that have left an indelible mark in the franchise. 

10. Haos In Resident Evil 6 

The creature is remarkable due to its enormous size, earning it a notable place as one of the largest monsters in the series.  Due to its size, it requires a substantial space on the screen.

9. The Ultimate Abyss In Resident Evil: Revelations

Defying expectations from a 3DS spin-off, Resident Evil: Revelations introduces an astonishing boss in the form of Jack Norman, The Ultimate Abyss. Unlike previous Tyrant-style matches, fighting against Jack Norman's mutant form requires more than just running and punching.

8. Super Tyrant In Resident Evil Remake 2

One of the most significant additions to the original Resident Evil 2 Remake is Mr. X, the Super Tyrant. Mr. X, who was once an enemy that was hidden for your second playthrough, now follows you around Raccoon City regardless of the playthrough you're on and it never stops chasing you.

7. Osmund Saddler In Resident Evil 4

Saddler is the enigmatic leader of the Los Illuminados cult. You spend most of the time walking around and doing very little until you finally find him obstructing your way out of the nightmare.

6. Osmund Saddler In Resident Evil 4 Remake

In Resident Evil 4 Remake, the final battle is one of the many things that have changed. Your opponent is still Saddler, just like you, but he's transformed into a mutant extra leg. He seems tougher and appears to take a lot more shots.

5. Nemesis In Resident Evil 3 Remake

There is controversy surrounding Resident Evil 3 Remake's final battle with Nemesis. Many were disappointed by the monstrosity that Nemesis turned into because it deviates so much from the original material. But don't let the doubters fool you.This Nemesis fight is absolutely amazing.

4. Alexia Ashford In Resident Evil: Code Veronica

The multi-stage battle against the surviving Ashford twin is brutal. Even the best players find it difficult to endure a fight that lasts for nearly five whole minutes in a game where they have very little ammunition. Alexia transforms into a variety of creatures throughout her many guises, starting as a twisted humanoid form and ending as a monstrous insect-like creature.

3. William Birkin In Resident Evil 2 Remake

The last battle with the tortured scientist William Birkin is a fantastic way to say goodbye to one of the most significant characters in the series. It is a great way to cap off the best campaign of Resident Evil 2 Remake.

2. Mother Miranda In Resident Evil: Village

The last confrontation between Resident Evil: Village and Miranda is quite unique . Ethan had enough after dying at Miranda's hands and then coming back to life moments later. After that, he finds out that he has caught the same illness that has corrupted the villagers he has been murdering for the previous two days.

1. Albert Wesker In Resident Evil 5

Probably the best final boss fight in the Resident Evil series is the final confrontation with Albert Wesker. Wesker, the final and most recognizable leader of Umbrella, is without a doubt the greatest antagonist Resident Evil has ever had and most likely will have ever.